Oral composition

ABSTRACT

Provided is a pumping type toothpaste product including a toothpaste composition. The toothpaste composition includes a polishing agent, and thus prevents the piston of a pumping type container from being worn by the polishing agent contained in the toothpaste composition so that the contents of the container may be ejected out smoothly. Also provided is a gel-like toothpaste composition having excellent viscosity retentivity. Further, provided is an oral composition showing high elasticity even at low viscosity, undergoing little change in viscosity with time and having significantly improved shape retentivity, flowability and dispersion stability through the synergic effect of xanthan gum and a thickening polymer.

FIELD

The present disclosure relates to an oral composition and a productincluding the same. More particularly, the present disclosure relates toa pumping type product including an oral composition, particularly atoothpaste composition, a gel-like toothpaste composition havingexcellent viscosity retentivity and an oral composition having excellentshape retentivity.

The present application claims priority to Korean Patent Application No.10-2013-0124515 filed on Oct. 18, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0069581 filed on Jun. 18, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0121397 filed on Oct. 11, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0069582 filed on Jun. 18, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0121408 filed on Oct. 11, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0069583 filed on Jun. 18, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0121417 filed on Oct. 11, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0069584 filed on Jun. 18, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

The present application claims priority to Korean Patent Application No.10-2013-0121432 filed on Oct. 11, 2013 in the Republic of Korea, thedisclosures of which are incorporated herein by reference.

BACKGROUND

In the case of paste-like toothpaste used most frequently among alltypes of toothpastes, it has high dispersion stability and is favorableto formulation of various pharmaceutically effective ingredients. Inaddition, it has high shape retentivity and is favorable to maintenanceof its shape after disposing toothpaste from the container thereof.However, such paste-like toothpaste has insufficient flowability due tohigh viscosity or the like, requires a large extent of force during itsejection from a tube to show inconvenience of use, and has lowreleasability to show a bad feeling of use.

Meanwhile, in the case of the conventional liquid toothpaste, it hasexcellent releasability but shows poor dispersion stability, and thus islimited in formulation of pharmaceutically effective ingredients.Moreover, in the case of such conventional liquid toothpaste, phaseseparation occurs during its distribution or use, resulting in loss ofcommodity value. In addition, it has insufficient shape retentivity,cannot retain a predetermined shape after disposing toothpaste onto atoothbrush, and infiltrates to the gap in the toothbrush, resulting ininconvenience of use.

Korean Patent Application No. 2001-7004081 discloses a liquid toothwashing gel having a controlled ratio of water to a wetting agent.However, the liquid tooth washing gel has problems related with shaperetentivity and flowability. In addition, Korean Patent Application No.2002-0053430 discloses improvement of shape retentivity and flowabilityusing sodium caseinate, but the degree of improvement is insufficient toprovide convenience of use to the users and sodium caseinate causesdegradation of quality in terms of sensibility. Moreover, in the case ofthe conventional high-viscosity paste type toothpaste or liquidtoothpaste, it is impossible to apply such toothpastes to various typesof containers. In the case of the high-viscosity paste type toothpaste,it is difficult to eject the toothpaste when using a dip tube type pumpand the toothpaste undergoes an increase in viscosity more with thelapse of time, leading to a failure in ejection. In the case of theconventional liquid toothpaste, it is not possible for the toothpaste toretain its shape even if it is ejected, leading to a failure in use.

The paste-like toothpaste that was developed first by Colgate Co. (USA)is sold in the form of an aluminum tube containing it. Even in 1970s′,such an aluminum tube was still used. Improvement from such a containerfor paste-like toothpaste to a currently used container made of analuminum laminate film is made by the development of polymer and polymerprocessing technology. However, in the case of such a tube typetoothpaste, there is a lot of inconvenience of use actually due to theresidual amount upon the ejection from a tube and high viscosity of apaste-like product. Then, in order to enhance convenience of use, therehas been an attempt to use a vacuum pump type plastic container so thathighly viscous paste may be ejected from the container. A part of suchproducts are on sale, but they have problems in terms of cost efficiencyand low releasability of the conventional paste-like toothpaste.

In general, sorbitol has been used as a wetting agent and moisturizerfor paste formulations.

In the case of sorbitol, it is used in the form of 70% solution.However, such solution may be transformed into a solid undesirably afterwater is dried. For this reason, there has been an attempt to providethe users with enhanced convenience of use by using a dispenser pump(dip pump) applied to shampoo or body wash. However, in the case of adispenser pump, the internal contents may be dried due to freecommunication with the external air when viewed from the characteristicsof the container, thereby causing an increase in viscosity and a failurein ejection. The internal contents may be even solidified, and thuscommercialization is limited severely.

Additionally, in the case of a toothpaste formulation, the polishingagent contained in the toothpaste has a Mohs hardness of about 3-6,which is higher than the hardness of low density polyethylene formingthe piston of a dispenser pump. Therefore, there is a problem in thatthe piston is worn by the polishing agent contained in the toothpaste,thereby making it difficult to eject the toothpaste. For this reason,there has been a need for preparing a toothpaste composition thatprovides high convenience of use like shampoo and body wash by using adispenser pump, and can be used without malfunction of a pump caused bywearing of a pump and solidification of internal contents.

Further, three has been a need for developing a toothpaste compositionthat solves the problem of sensational displeasure as well as theproblem of solidification, while allowing application to a dip pump.

Meanwhile, according to the related art, a liquid toothpaste producthaving flowability in a plastic container has been launched to improvereleasability of toothpaste. However, such a product flows on atoothbrush and has a difficulty in transferring the active ingredientsof the toothpaste product to teeth and gum effectively. Moreover, such aliquid toothpaste product may be dried as it is in contact with the airrepeatedly, resulting in the problem of an increase in viscosity.

The liquid toothpaste according to the related art causes solidificationof internal contents as the viscosity increases, and cannot retain itsoriginal form to cause inconvenience of use.

Therefore, active studies have been conducted to prevent solidificationof internal contents while maintaining convenience of use of theconventional liquid toothpaste.

DISCLOSURE Technical Problem

The present disclosure is designed to solve the problems of the relatedart, and therefore the present disclosure is directed to providing atoothpaste composition applicable to a pumping type (dispenser pump)container and a pumping type toothpaste product including the toothpastecomposition.

Particularly, the present disclosure is directed to providing atoothpaste composition that causes a reduced degree of wearing of apiston in a pumping type container and a toothpaste product includingthe same.

In addition, the present disclosure is directed to providing atoothpaste composition that can be used without solidification caused bya change in viscosity to provide improved convenience of use.

In addition, the present disclosure is directed to providing a gel typetoothpaste composition capable of solving the above-mentioned problemsand having excellent viscosity retentivity.

In addition, the present disclosure is directed to providing atoothpaste composition that can be pumped even in a container such as adip pump without a rapid increase in viscosity and solidificationdespite the use of a sugar alcohol and can alleviate a bitter taste interms of sensibility.

In addition, the present disclosure is directed to providing an oralcare composition having high shape retentivity and improved flowabilityand dispersion stability.

Further, the present disclosure is directed to providing an oralcomposition that has elasticity even at low viscosity, shows littlechange in viscosity with time, has significantly improved shaperetentivity, flowability and dispersion stability, and thus can beapplied to various containers and uses.

Technical Solution

In one aspect of the present disclosure, there is provided a pumpingtype toothpaste product including a toothpaste composition, wherein thecomposition includes a lubricant.

To solve the above mentioned problems, there is provided a pumping typetoothpaste product including a lubricant and polishing agent.Preferably, there is provided a pumping type toothpaste productincluding a polishing agent and using a lubricant in combination toprevent a piston from wearing caused by the polishing agent, and thusproviding convenience of use.

As used herein, the term ‘pumping type or dispenser pump’ is referred toas a structure capable of ejecting the contents stored in a containerthrough an ejection port by way of pumping action using the pushingportion of the container. Particularly, the term means a structure withwhich the toothpaste composition present in the container is ejected outof the container through the pumping action of the piston. In otherwords, the contents may be discharged from the bottom of the inner partof the container to the exterior thereof by the piston mounted to theinside of the container through pumping action.

Meanwhile, in general, the piston may be worn by the polishing agentcontained in a toothpaste composition so that the contents may not beejected smoothly. Thus, application of such a toothpaste compositionusing a pumping type container is limited although it is convenient touse.

Therefore, the inventors of the present disclosure have conducted manystudies to obtain a pumping type toothpaste product which prevents thewearing of a piston caused by a polishing agent, prevents solidificationof contents caused by the contact with the external air, and isconvenient to use. The present disclosure is finished from the studies.

The toothpaste composition disclosed herein may include a polishingagent. The polishing agent contained in the toothpaste composition is amaterial functioning to remove dental plaque, is essentially used toincrease the removal efficiency of dental plaque and to remove hardforeign materials, and has a Mohs hardness of about 3-6.

The polishing agent is present in an amount of 0.1-30 wt %, preferably0.5-20 wt %, based on the total weight of the toothpaste composition ofthe toothpaste product containing the same. When the amount of thepolishing agent is less than 0.1 wt %, it is difficult for thetoothpaste to provide a polishing effect, resulting in poor plaquecleaning quality. When the amount of the polishing agent is larger than30 wt %, excessive wearing of a piston may occur and a pump can hardlyrealize its performance.

The polishing agent may include any one selected from the groupconsisting of calcium monohydrogen phosphate, precipitated silica, fumedsilica, colloidal silica, zeolite, calcium carbonate, hydrous alumina,kaolin, cellulose and a mixture thereof.

A polishing agent is generally used in a toothpaste composition toremove dental plaque or the like. When a toothpaste composition isprovided in a pumping type product, wearing of a piston may occur due tothe hardness of the polishing agent. Such a problem occurs because thepiston is made of low density polyethylene and the hardness ofpolyethylene is lower than the hardness of the polishing agent used inthe product.

The lubricant means a material with which the friction between twosliding surfaces contacting with each other is decreased. As usedherein, the lubricant provides a lubricating function and thus preventswearing of a piston caused by a material (solid content such as apolishing agent) having wearing property and contained in the toothpastecomposition disclosed herein.

Particularly, petroleum-based oil, animal or vegetable oil, syntheticoil etc. may be used as liquid lubricant. More particularly, a liquidpolyol may be used in view of the stability and good feeling of use of acomposition.

The liquid polyol means a polyol present as liquid at room temperature,while not showing wetting property upon dissolution into water likesugar alcohol.

The lubricant may be present in an amount of 30-85 wt %, particularly40-75 wt % based on the total weight of the toothpaste compositiondisclosed herein.

When the amount of the lubricant is less than 30 wt %, the toothpastecomposition may be solidified with ease, the polishing agent may causedamage on a piston and the contents cannot be ejected to the exteriorsmoothly, and the lubricant may impart a stiff feeling of use and causeinconvenience of use. On the other hand, when the amount of thelubricant is larger than 85 wt %, the proportion of liquid ingredientsin the total toothpaste composition is too low to show viscosity, andthus the toothpaste composition may flow undesirably like theconventional liquid toothpaste.

The lubricant may include any one selected from the group consisting ofpolyethylene glycol, glycerol, propylene glycol, ethylene glycol,polypropylene glycol and a mixture thereof. Particularly, the lubricantmay include any one selected from the group consisting of polyethyleneglycol 200-600, glycerol, propylene glycol, ethylene glycol,polypropylene glycol and a mixture thereof. In addition, the lubricantis not limited to a liquid polyol but includes a high-molecular weightpolyol that may be liquefied, commercialized and retained in a stablestate although it may be present as solid at room temperature due to theintramolecular interaction of a polymer at a molecular weight higherthan a predetermined level, like polyethylene glycol or polypropyleneglycol in the form of a polymer.

The inventors of the present disclosure have found that when atoothpaste composition including a polishing agent is used incombination with a liquid polyol, the toothpaste composition does notcause solidification resulting from a change in viscosity and mayprovide a good feeling of use. The present disclosure is based on thisfinding.

In another aspect, there is provided a toothpaste composition includinga polishing agent in combination with a liquid polyol, the toothpastecomposition causing no solidification resulting from a change inviscosity and providing a good feeling of use. There is also provided apumping type toothpaste product including the same.

As used herein, the term ‘viscosity’ means an extent of viscous propertyof a toothpaste composition. In addition, ‘viscosity retentivity’ meanshow much the viscosity of a composition upon its preparation is retainedconstantly after least 2 years. Particularly, viscosity retentivitymeans a change in viscosity of about 100-15,000 cP after at least 2years as compared to the viscosity upon the preparation, when viscositymeasurement is carried out under the conditions of 25° C., 20 rpm and 5cycles, by using BrookField RVT spindle No. 7 or RV-5.

In still another aspect, there is provided a toothpaste composition foruse in a pumping type container, the toothpaste composition includingboth a sugar alcohol and a liquid polyol. Particularly, there areprovided a toothpaste composition wherein both the sugar alcohol andliquid polyol are used in a pumping type container so that the contentsmay retain predetermined viscosity and the problem of drying may beovercome, and a pumping type toothpaste product including the toothpastecomposition.

The inventors of the present disclosure have found that when atoothpaste composition is in direct contact with the external air as inthe case of a pumping type container, it may be solidified with ease andmay not function as toothpaste. The present disclosure solves theabove-mentioned problem.

Particularly, we have found that although the sugar alcohol used as amoisturizing ingredient for a toothpaste composition has a moisturizingeffect, it causes easy solidification of the composition upon theevaporation of water that is in contact with the composition.

To solve the above-mentioned problem, according to the presentdisclosure, the sugar alcohol contained in the toothpaste composition isallowed to react with a liquid polyol to carry out encapsulation so thatthe liquid polyol may surround the sugar alcohol and the sugar alcoholmay not be exposed.

The reason why the liquid polyol and sugar alcohol are present in anencapsulated structure is that the hydroxyl or ether groups of a liquidpolyol and the hydroxyl groups of a sugar alcohol form hydrogen bondingwith each other.

The inventors of the present disclosure have thought that such hydrogenbonding solves the problem related with ejection caused bysolidification and a rapid change in viscosity. The present disclosureis based on this thought.

The sugar alcohol is also referred to as solid polyol or solidifyingpolyol and may include erythritol, arabitol, xylitol, ribitol, sorbitol,mannitol, galactitol, maltitol, lactitol or a mixture thereof.Particularly, sorbitol may be used in any form selected from sorbitolsolution, amorphous sorbitol and crystalline sorbitol with no particularlimitation.

The sugar alcohol may be used in an amount of 1-70 wt %, particularly1.5-65 wt %, and more particularly 2-60 wt %, based on the total weightof the composition.

When the sugar alcohol is used in an amount less than 1 wt %, it is notpossible to improve the quality in terms of sensibility despite the useof a sugar alcohol. When the sugar alcohol is used in an amount largerthan 70 wt %, the toothpaste composition may be solidified undesirably.

To accomplish the objects of the present disclosure, the liquid polyolused in combination with the sugar alcohol to maintain the viscosity ofa toothpaste composition constantly and to prevent solidification of thecontents may be polyethylene glycol 200-600, glycerol, propylene glycol,ethylene glycol, polypropylene glycol or a mixture thereof.Particularly, the liquid polyol may be glycerol, polyethylene glycol 300or a mixture thereof.

The liquid polyol may be used in an amount of 10-85 wt % based on thetotal weight of the composition. In addition, the molar ratio of thehydroxyl or ether groups of the liquid polyol forming hydrogen bondingwith the hydroxyl groups of the sugar alcohol may be at least 0.2.

When the liquid polyol is used in an amount larger than 85 wt % based onthe total weight, it is not possible to carry out formulation. When theliquid polyol is used in an amount less than 10 wt % or when hydrogenbonding is formed at a proportion less than 0.2, the compositiondisclosed herein may undergo solidification or a rapid increase inviscosity upon the application thereof to a dip pump.

When the liquid polyol has a high content ratio of hydroxyl groups tocarbon but has a low molecular weight, as in the case of glycerin orpropylene glycol, the sugar alcohol and liquid polyol show stronghydrogen bonding force. However, in this case, there is a problem inthat reseparation and rearrangement caused by vapor pressure may occurwith ease. Thus, it is possible to solve the problems of solidificationof a toothpaste composition and a rapid change in viscosity within theabove-defined ratio.

In addition, when the liquid polyol has a large molecular weight as inthe case of polyethylene glycol, a high-molecular weight liquid polyoland the sugar alcohol participate in hydrogen bonding, resulting inencapsulation of the sugar alcohol. When the molar ratio of the hydroxylgroups of the sugar alcohol to the hydroxyl or ether groups of theliquid polyol is at least 1:0.2, it is possible to inhibitsolidification or a rapid increase in viscosity.

For example, as shown in FIG. 1, this may be exemplified by sorbitol.

Sorbitol has six carbon atoms to which six hydroxyl groups are bound.When sorbitol is in contact with water, six water molecules formhydrogen bonding to one sorbitol molecule to produce crystal water. Whenthe formed crystal water evaporates partially or totally, it shows acrystalline form and is solidified.

Therefore, according to an embodiment of the present disclosure in whicha toothpaste composition is used for a dip pump, at least one hydroxylgroup of the six hydroxyl groups covalently bonded to six carbon atomscontained in one sorbitol molecule is allowed to form hydrogen bondingwith a liquid polyol so that solidification or a rapid increase inviscosity may be inhibited.

In addition to the polishing agent and lubricant, the toothpastecomposition may further include conventional ingredients, such as afragrance ingredient, sweetener, pharmaceutically active ingredient, pHadjusting agent, preservative, binder, bubbling agent, whitener, or thelike, depending on formulation and use. The composition according to thepresent disclosure may include a fragrance ingredient and sweetener tomeet the consumer's preference. A fragrance ingredient remains in theoral cavity and emits fragrance continuously so that a feeling ofbreeziness may be continued.

Particular examples of the fragrance ingredient that may be used hereininclude a mint such as peppermint or spearmint, wintergreen, methylsalicylate, eugenol, melon, strawberry, orange, vanillin, or the like.

In general, a fragrance ingredient may be used in an amount of 0.001-10wt % based on the total weight of the composition.

In addition, a sweetener may be added to the composition disclosedherein to overcome the basic taste of the formulation. Such a sweetenerprovides a taste while it remains in the oral cavity, thereby allowingcontinuance of the generation of saliva.

Particular examples of the sweetener that may be used herein includesaccharin, sucralose, sugar, xylitol, sorbitol, lactose, mannitol,maltitol, erythritol, aspartame, taurine, saccharin salt, D-tryptophanor a mixture thereof. Sodium saccharin is used most widely amongsaccharine salts. In general, such a sweetener may be used in an amountof 0.001-20 wt % based on the total weight of the composition. Apharmaceutically active ingredient is one for use in oral hygiene, andmay include ingredients effective for preventing dental caries, gumdiseases and plaque deposition and for whitening. Particular examples ofa pharmaceutically active ingredient effective for preventing dentalcaries include fluoride-containing stable compounds approved as a safematerial by FDA. Particular examples of the compound that may be used asa source for fluoride include sodium fluoride, sodiummonofluorophosphate, tin fluoride, ammine fluoride, or the like. Thefluorine content may be varied with nations. Particularly, at least oneof such sources may be used to provide a fluoride concentration of850-1500 ppm. In general, such sources are used alone or in combination.A recalcification agent may also function as an agent for preventingdental caries. Recalcification serves to regenerate and recoverhydroxyapatite, one of the main ingredients forming teeth. Mainingredients of hydroxyapatite include divalent calcium cation andphosphate anion. Therefore, the recalcification agent may be a compoundthat contains at least one of divalent calcium ion and phosphate anionso that calcium ion and phosphate ion may be supplied at the same timeand the chemical equilibrium in the oral cavity may be shifted towardthe production of hydroxyapatite. Particular examples of a material thatprovides calcium and phosphorus may include a raw material ofhydroxyapatite, calcium hydrogen phosphate, calcium chloride, caseinphosphopeptide, calcium glycerophosphate, sodium dihydrogen phosphate,sodium hydrogen phosphate, trisodium phosphate, potassium dihydrogenphosphate, potassium hydrogen phosphate, tripotassium phosphate, or thelike. In general, such a recalcification agent may be used in an amountof 0.001-20 wt % based on the total weight of the composition. When theamount of recalcification agent is less than 0.001 wt %, it is notpossible to provide a sufficient recalcification effect. When the amountof recalcification agent is larger than 20 wt %, the resultantformulation may lose its unique properties. One of the purposes of oralhygienic products is alleviating ongoing gum diseases or preventing gumdiseases through the sterilization or anti-inflammation of harmful oralmicroorganisms living in the oral cavity. For this purpose, a knownantibacterial agent, such as isopropylmethylphenol, cyclohexidin,cetylpyridinium chloride, triclosan or xantolisol, may be used. As ananti-inflammatory agent, vitamins, enzymes, aminocaproic acid, allantoinand derivatives thereof may be used. Such a pharmaceutically activeagent may be present in an amount of 0.005 wt %-5 wt %. When thepharmaceutically active agent is present in an amount less than 0.005 wt%, it is difficult to realize a pharmaceutical effect. When thepharmaceutically active agent is present in an amount larger than 5 wt%, the formulation base undergoes a change in taste. It is also possibleto use hydrogen peroxide, carbamide peroxide or calcium peroxide thatshows a whitening effect in addition to an effect of alleviating orpreventing gum diseases. In addition, sodium pyrophosphate, acidicsodium pyrophosphate, potassium pyrophosphate or sodium metaphosphate isused to obtain an effect of inhibiting plaque deposition. In general,such a pharmaceutically active ingredient is used in an amount of0.001-10 wt % based on the total weight of the composition. As a pHadjusting agent, phosphoric acid, sodium phosphate, citric acid, sodiumcitrate, fumaric acid, sodium fumarate, tartaric acid or sodium tartratemay be used. In general, the acidity of an oral composition is 5-8. As abinder, sodium carboxymethyl cellulose, carbomer, carrageenan, xanthangum or alginate may be used alone or in combination. Such a binder isused generally in an amount of 0.1-5 wt %, particularly 0.5-3 wt %,based on the total weight of the oral composition. As a preservative,benzoic acid, methyl paraben, propyl paraben or sodium benzoate may beused. As a bubbling agent, anionic, amphoteric or non-ionic surfactant,such as sodium alkylsulfonate, sodium laurylsulfonate, alkylsarcosinate, lauryl sarcosinate, sodium cocoyl glutamate, sodiummyristoyl glutamate, cocamidopropyl betain, sucrose fatty acid ester,sorbitan fatty acid ester, polyoxyethylene-co-polyoxypropylene(Poloxamer), may be used alone or in combination.

As a brightening agent, titanium dioxide is used, suitably in an amountof 0.1-2 wt %. The toothpaste composition disclosed herein may beobtained by a method generally known to those skilled in the art.

In still another aspect, there is provided a gel-like toothpastecomposition including a polishing agent and liquid polyol. Particularly,the novel gel-like toothpaste composition uses a polishing agent andliquid polyol together so that the contents may maintain predeterminedviscosity and a drying phenomenon may be improved.

As used herein, the term ‘gel formulation’ or ‘gel-like’ is used as theconcept different from the conventional diluted liquid toothpaste andhighly viscous paste-like toothpaste. The gel formulation is onedistinguished from the conventional liquid formulation and has highertackiness and viscosity. The gel-like toothpaste disclosed herein haselasticity and shows rigidity unlike a liquid toothpaste. In addition,the gel-like toothpaste has lower viscosity than paste type toothpasteand is fluidic, and shows flowability to allow easy ejection of thecontents to the exterior.

The gel formulation disclosed herein is little diluted, unlike theconventional liquid toothpaste. Thus, when the user applies thetoothpaste disclosed herein to a toothbrush, the toothpaste does notflow but is positioned stably on the toothbrush, thereby providing anexcellent feeling of use to the user. Particularly, the gel-liketoothpaste composition disclosed herein allows the finished toothpasteproduct to have a viscosity of about 5,000-36,000 cps as determined byusing BrookField, RVT Type, No. 7 spindle under the conditions of 25°C., 20 rpm, 5 cycles.

The types of the polishing agent and liquid polyol contained in such agel-like toothpaste composition are not particularly limited, as long asthey are used for the pumping type toothpaste product disclosed herein.

The amounts of the polishing agent and liquid polyol are the same as inthe pumping type toothpaste product. Particularly, the liquid polyol maybe used in an amount selected adequately within the range used in thepumping type toothpaste product, considering the easy ejectability ofthe contents, viscosity of the contents or phase separation of thepolishing agent.

The gel-like toothpaste composition may further include conventionalingredients that may be contained in the conventional liquid toothpastecomposition in addition to the polishing agent and liquid polyol. Suchconventional ingredients may include a fragrance ingredient, sweetener,pharmaceutically active ingredient, pH adjusting agent, preservative,binder, bubbling agent, brightener, or the like.

In still another aspect, there is provided an oral composition providedwith elasticity based on xanthan gum.

The expression ‘provided with elasticity based on xanthan gum’ meansthat xanthan gum affects the elasticity of an oral composition. Theexpression ‘based on xanthan gum’ means that xanthan gum has a maineffect upon the characteristics of an oral composition, particularlyupon the shape and characteristics of the oral composition disclosedherein.

In other words, there is provided an oral composition containing xanthangum and having elasticity. Particularly, there is provided a toothpastecomposition containing xanthan gum and a thickening polymer and showingelasticity even at low viscosity.

As used herein, the term ‘oral composition’ may include toothpaste,mouthwash, dentures cleaner, or the like. Particularly, the term ‘oralcomposition’ means a toothpaste composition.

More particularly, there is provided an oral composition, particularly atoothpaste composition, which undergoes little change in viscosity withtime and has excellent shape retentivity, flowability and dispersionstability. In addition, the composition having improved shaperetentivity, flowability and dispersion stability has no particularlimitation in uses and containers, and thus may be applied to varioustypes of products.

The inventors of the present disclosure have found that the presence ofxanthan gum, particularly the combination of xanthan gum with athickening polymer, provides a toothpaste composition with excellentelasticity and improved shape retentivity. The present invention isbased on this finding.

Therefore, the oral composition disclosed herein is not limited in itscontainer upon use. However, the oral composition may be applied to apumping type container by virtue of the above-mentioned physicalproperties, and thus provides convenience of use.

As used herein, the term ‘elasticity’ means the ability of a material toreturn to its original shape after it has been deformed by externalforce and then the force has been removed, and is used in its broadconcept referring to the property of a material to maintain its originalshape. In other words, the term is used in its broad meaning includingall properties to maintain the original shape and height after atoothpaste composition is ejected from an ejection port.

In addition, the inventors of the present disclosure have found thatincorporation of xanthan gum, particularly xanthan gum and a thickeningpolymer to a toothpaste composition solves the problem of theconventional high-viscosity paste-like product, including lack offlowability and requirement for excessive force upon the ejection of theproduct from its tube. Further, we have found that it is possible toimprove the problems related with dispersion stability and shaperetentivity occurring in the conventional liquid toothpaste. The presentdisclosure is based on these findings.

Particularly, the present disclosure provides an oral composition,particularly a toothpaste composition, capable of retaining apredetermined shape even at low viscosity to solve the problemsoccurring in both paste type toothpaste and conventional liquidtoothpaste.

As used herein, the term low viscosity′ means about 5,000-20,000 cps asdetermined by using BrookField, RV-5 under the conditions of 25° C., 20rpm, particularly by using BrookField, RV-5 under the conditions of 25°C., 20 rpm, 5 cycles.

In addition, the term ‘high viscosity’ means at least a viscosity notdetermined under the conditions of BrookField, RV-5, 25° C., 20 rpm.

The thickening polymer may include at least one selected from the groupconsisting of starch, carbomer, gellan gum, gelatin, guar gum, locustbean gum, alginic acid, Arabic gum, carrageenan, agar, pectin, rheogic,cellulose and derivatives thereof.

The cellulose and derivatives thereof include any one selected from thegroup consisting of sodium carboxymethylcellulose, hydroxymethylcellulose, hydroxypropylmethyl cellulose, methylethyl cellulose and amixture thereof.

The toothpaste composition disclosed herein may include xanthan gum inan amount larger than 0.5 wt % and less than 3 wt %, particularly in anamount of 1-2.8 wt %, more particularly 1.5-2.5 wt %.

When xanthan gum is used in an amount of 0.5 wt % or less, thetoothpaste composition is in the form of liquid, and thus it is notpossible to impart sufficient elasticity. When xanthan gum is used in anamount of 3 wt % or more, cost efficiency is degraded as compared toimprovement of effect and the toothpaste composition has high viscosity,resulting in inconvenience of use.

In addition, the toothpaste composition may further include a thickeningpolymer in an amount of 0.05-1 wt % based on the total weight of thecomposition.

When the thickening polymer is used in an amount less than 0.05 wt %, itis not possible to impart sufficient elasticity. When the thickeningpolymer is used in an amount larger than 1 wt %, cost efficiency isdegraded as compared to improvement of effect and the toothpastecomposition has high viscosity, resulting in inconvenience of use.

The toothpaste composition disclosed herein may have a viscosity of5,000-20,000 cP as determined by using BrookField, RV-5 under theconditions of 25° C., 20 rpm, and particularly a viscosity of5,000-20,000 cP as determined by using BrookField, RV-5 under theconditions of 25° C., 20 rpm, 5 cycles.

The oral composition having the above-defined range of viscosity isfound to have excellent shape retentivity when it is formed into aproduct. Particularly, it has been found that when the oral compositionis a toothpaste composition, it has excellent shape retentivity andconvenience of use. The present disclosure is based on this finding.

Particularly, when the composition is received in a container having adiameter of 0.3-1.0 cm and is ejected to an area of width 2 cm×length 1cm in an amount of 1 g, it has an initial height of 0.15-0.55 cm and aheight of 0.1-0.45 cm after 30 seconds. The inventors of the presentdisclosure have found that the toothpaste composition disclosed hereinhas the above-mentioned characteristics, shows elasticity even at aviscosity lower than the viscosity of the conventional paste-liketoothpaste and undergoes a very small change in viscosity with time.

The oral composition disclosed herein may further include variousingredients in addition to xanthan gum and a thickening polymeraccording to its formulation. When the oral composition is toothpaste,it may further include a wetting agent, polishing agent, fragranceingredient, sweetener, pharmaceutically active ingredient, pH adjustingagent, preservative, bubbling agent, brightening agent or the like.

The toothpaste composition disclosed herein may be obtained by a methodgenerally known to those skilled in the art.

Advantageous Effects

The present disclosure gives the following effects.

The toothpaste composition disclosed herein uses a pumping typecontainer and provides convenience of use.

The conventional toothpaste composition may not be applied to a pumpingtype container despite its good feeling of use and has the problems ofsolidification caused by the contact with air or a rapid change inviscosity. The present disclosure solves the above-mentioned problems.

According to the present disclosure, it is possible to improve thewearing of the piston of a pumping type container due to a polishingagent. Thus, it is possible to provide a toothpaste composition andpumping type toothpaste product capable of ejecting the contentssmoothly to the exterior of the container.

Therefore, according to the present disclosure, pumping type containersthat have high cost efficiency and are manufactured with ease may beapplied instead of vacuum pump type containers requiring high cost. As aresult, it is possible to reduce the manufacturing cost.

Particularly, according to the present disclosure, a liquid polyolhaving low sensational quality is combined with a sugar alcohol toprovide excellent sensational quality while solving the problem ofsolidification of toothpaste.

In addition, the present disclosure provides a gel-like toothpastecomposition having an excellent feeling of use and high viscosityretentivity.

The gel-like toothpaste composition improves the disadvantages of aliquid toothpaste composition, including solidification caused by thecontact with air, a rapid change in viscosity and inconvenience of use.

Further, the oral composition disclosed herein, particularly toothpastecomposition, has high elasticity even at low viscosity.

According to the present disclosure, there is provided an oralcomposition, particularly toothpaste composition, which causes littlechange in viscosity with time and has significantly improved shaperetentivity, flowability and dispersion stability.

According to the present disclosure, it is possible to solve theproblems of the conventional paste-like toothpaste and liquidtoothpaste, and to provide an oral composition applicable to varioustypes of containers and various uses.

In addition, there are provided an oral composition having physicalproperties applicable to a pumping type container, and a pumping typetoothpaste product.

DESCRIPTION OF DRAWINGS

Other objects and aspects of the present disclosure will become apparentfrom the following descriptions of the embodiments with reference to theaccompanying drawings in which:

FIG. 1 is a schematic view illustrating the mechanism by which glycerinprevents direct contact between sorbitol and water.

FIG. 2 is a schematic view illustrating the mechanism by which ahigh-molecular weight liquid polyol, polyethylene glycol 300, minimizesdirect contact between a sugar alcohol and water.

FIG. 3 is a toothpaste ejection table showing the shape retentivity ofeach toothpaste composition.

FIG. 4 is an image showing the pumps damaged by inadequate ejection ofcontents from pumping type containers.

FIG. 5 shows a questionnaire prepared to allow consumers to evaluate thetoothpaste compositions.

FIG. 6 is a diagram illustrating the evaluation results for toothpastecompositions after the evaluation of consumers.

BEST MODE

Hereinafter, preferred embodiments of the present disclosure will bedescribed in detail with reference to the accompanying drawings. Priorto the description, it should be understood that the terms used in thespecification and the appended claims should not be construed as limitedto general and dictionary meanings, but interpreted based on themeanings and concepts corresponding to technical aspects of the presentdisclosure on the basis of the principle that the inventor is allowed todefine terms appropriately for the best explanation. Therefore, thedescription proposed herein is just a preferable example for the purposeof illustrations only, not intended to limit the scope of thedisclosure, so it should be understood that other equivalents andmodifications could be made thereto without departing from the scope ofthe disclosure.

I. Examples 1-12 and Comparative Examples 1-4 1. Composition andPreparation Examples 1-6 and Comparative Examples 1-2

Each of the toothpaste compositions according to Examples andComparative Examples is obtained from the ingredients and compositionsas shown in the following Table 1. Powdery ingredients including apharmaceutically active ingredient, xanthan gum, saccharin, preservativeand surfactant are dispersed completely into liquid ingredientscontaining purified water, glycerin and fragrance, and mixed primarily.Then, a polishing agent, such as silica, and a pharmaceutically activeingredient are introduced thereto and mixed under vacuum to obtaintoothpaste compositions.

In Table 1, the amount of each ingredient is expressed in the unit of wt%.

TABLE 1 Comp. Comp. Ex. 1 Ex. 2 Ex. 3 Ex. 4 Ex. 5 Ex. 6 Ex. 1 Ex. 2Precipitated silica 1.00 5.00 10.00 20.00 20.00 20.00 Calcium carbonate30 Calcium hydrogen 30 phosphate Glycerin 45.00 45.00 45.00 45.00 45.0045.00 10.00 70% sorbitol solution 45.00 45.00 Sodium laurylsulfonate2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 Sodium saccharin 0.20 0.20 0.200.20 0.20 0.20 0.20 0.20 Paraoxybenzoate 0.15 0.15 0.15 0.15 0.15 0.150.15 0.15 Xantan gum 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Sodiumfluoride 0.22 0.22 0.22 0.22 0.22 0.22 Sodium monofluoro 0.76 0.76phosphate Vitamin E 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Fragrance1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Purified water 49.23 45.23 40.2330.23 19.69 19.69 20.23 30.23

Examples 7-12 and Comparative Examples 3-4

Each of the toothpaste compositions according to Examples andComparative Examples is obtained from the ingredients and compositionsas shown in the following Table 2. Powdery ingredients including apharmaceutically active ingredient, xanthan gum, saccharin, preservativeand surfactant are dispersed completely into liquid ingredientscontaining purified water, polyethylene glycol 300, glycerin andpropylene glycol, and mixed primarily. Then, a polishing agent, such assilica, and a pharmaceutically active ingredient are introduced theretoand mixed under vacuum to obtain toothpaste compositions.

TABLE 2 Comp. Comp. Ex. 7 Ex. 8 Ex. 9 Ex. 10 Ex. 11 Ex. 12 Ex. 3 Ex. 4Precipitated silica 15.00 15.00 15.00 15.00 15.00 15.00 20.00 15.00Polyethylene glycol 300 60.00 5 40 5 Glycerin — 60.00 55 50 20.00Propylene glycol 60.00 20 5 Sorbitol — 60.00 Sodium laurylsulfonate 2.002.00 2.00 2.00 2.00 2.00 2.00 2.00 Sodium saccharin 0.20 0.20 0.20 0.200.20 0.20 0.20 0.20 Paraoxybenzoate 0.15 0.15 0.15 0.15 0.15 0.15 0.150.15 Xanthan gum 1.50 1.50 1.50 1.50 1.50 1.50 1.00 1.50 Sodium fluoride0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 Vitamin E 0.20 0.20 0.20 0.200.20 0.20 0.20 0.20 Fragrance 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00Purified water 19.73 19.73 19.73 19.73 19.73 19.73 55.23 19.73

2. Change in Viscosity with Time

The following test is carried out to observe a change in viscosity withtime for each of the toothpaste compositions according to Examples andComparative Examples listed in Table 1 and Table 2.

(1) Determination of Viscosity

Each of the toothpastes obtained according to Examples 1-12 andComparative Examples 1-4 listed in Table 1 and Table 2 is tested rightafter its preparation and after 1 months and 12 months in a pumping typecontainer by determining a change in viscosity. Determination ofviscosity is carried out by using Brookfield viscometer RVT type,spindle No. 7 under a rotation speed of 10 rpm. The results are shown inthe following Table 3.

TABLE 3 Viscosity (X 1000 cP) Initial time 1 month 12 months Ex. 1 34 3535 Ex. 2 32 36 35 Ex. 3 32 32 39 Ex. 4 33 35 37 Ex. 5 34 37 37 Ex. 6 3236 37 Ex. 7 31 35 38 Ex. 8 33 32 35 Ex. 9 32 35 35 Ex. 10 33 36 36 Ex.11 31 32 35 Ex. 12 33 36 38 Comp. Ex. 1 35 51 Solidified Comp. Ex. 2 3555 Solidified Comp. Ex. 3 35 45 200 or more Comp. Ex. 4 35 81 Solidified

According to Comparative Examples 1 and 2 using sorbitol, thetoothpastes are solidified after the lapse of 12 months at roomtemperature and viscosity cannot be determined. In addition, in the caseof Comparative Examples 1 and 2, a rapid change in viscosity is observedafter 1 month due to the evaporation of water.

However, as can be seen from the results of Examples 1-4, no significantchange in viscosity is observed even when the amount of a polishingagent increases. This suggests that the amount of a polishing agent hasno significant effect upon a change in viscosity with time.

In addition, as can be seen from the results of Examples 8 and 9,incorporation of glycerin and propylene glycol causes no significantchange in viscosity with time.

According to the results of Comparative Example 3, when glycerin ispresent in an amount of about 20 wt %, a significant change in viscosityoccurs with time.

According to the results of Comparative Example 1, incorporation of botha small amount of glycerin and a solid lubricant causes a rapid increasein viscosity, and then results in solidification after the lapse of along time. It is thought that a small amount of liquid polyol allows thetoothpaste composition to maintain ejection property at the initial timebut it is difficult to eject the contents as time goes by.

It can be seen from the above test results that the toothpastecomposition disclosed herein undergoes little change in ejectionproperty caused by a rapid change in viscosity, when it is applied to adip pump.

In addition, it can be seen that the combination of a liquid polyol witha polishing agent allows the use of a dip pump even in an air permeablecontainer without any rapid change in viscosity and solidification.

(2) Ejection from Dip Pump

Each of the toothpaste compositions according to Examples 1-12 andComparative Examples 1-4 is received in a 250 mL pump container andpumping is carried out continuously so that the remaining amount may be20 gram or less to evaluate the ejection property. The results are shownin the following Table 4.

TABLE 4 Ejection Property Initial time 1 month 12 months Ex. 1 Ejectionfinished Ejection finished Ejection finished Ex. 2 Ejection finishedEjection finished Ejection finished Ex. 3 Ejection finished Ejectionfinished Ejection finished Ex. 4 Ejection finished Ejection finishedEjection finished Ex. 5 Ejection finished Ejection finished Ejectionfinished Ex. 6 Ejection finished Ejection finished Ejection finished Ex.7 Ejection finished Ejection finished Ejection finished Ex. 8 Ejectionfinished Ejection finished Ejection finished Ex. 9 Ejection finishedEjection finished Ejection finished Ex. 10 Ejection finished Ejectionfinished Ejection finished Ex. 11 Ejection finished Ejection finishedEjection finished Ex. 12 Ejection finished Ejection finished Ejectionfinished Comp. Ex. 1 150 mL  80 mL Not ejectable Comp. Ex. 2 200 mL 120mL Not ejectable Comp. Ex. 3 200 mL 115 mL Not ejectable Comp. Ex. 4 150mL  80 mL Not ejectable

In addition, ejection property is evaluated according to the amount ofsorbitol used in Comparative Examples and the amount of a polishingagent. After the evaluation, it is shown that the toothpastes accordingto Comparative Examples cannot be ejected any longer even at low initialviscosity, after ejecting about 150 mL. It is thought that the piston ina dip pump is worn by a polishing agent and thus complete ejectioncannot be carried out. After 1 month where the viscosity increases, theejection amount is decreases by about 50% due to the wearing of a pistoncaused by a polishing agent and the viscosity increases. After 1 year,the toothpastes are solidified and thus cannot be ejected any longer.

In the case of Comparative Examples 2 and 3 using glycerin in an amountof critical concentration or lower, they initially show anti-wearingproperty and allow sufficient ejection as compared to Examples usingsorbitol alone. However, Comparative Examples 2 and 3 finally cause arapid decrease in ejection amount due to an increase in wearing ratewith time.

It can be seen from the above results that a polishing agent and asolidifying polyol lead to damages on the piston of a pump and anincrease in viscosity, thereby causing a failure in ejection.

On the contrary, when using at least one selected from polyethyleneglycol 300, glycerin and propylene glycol, continuous ejection isallowed with time regardless of the presence of a polishing agent. Thissuggests that at least one selected from polyethylene glycol 300,glycerin and propylene glycol functions as a lubricant and solves theproblems of solidification, an increase in viscosity and wearing causedby a polishing agent.

II. Examples 13-22 and Comparative Examples 5-8 1. Composition andPreparation Examples 13-17 and Comparative Examples 5-6

Each of the toothpaste compositions according to Examples andComparative Examples is obtained from the ingredients and compositionsas shown in the following Table 5. A liquid polyol is mixed with a solidpolyol (or a sugar alcohol) first to induce hydrogen bonding, and thenpowdery ingredients including a pharmaceutically active ingredient,xanthan gum, saccharin, preservative and surfactant are dispersedcompletely into the solution of purified water and a fragranceingredient, followed by further mixing. Then, if desired, a polishingagent, such as silica, and a pharmaceutically active ingredient areintroduced thereto and mixed under vacuum to obtain toothpastecompositions.

In Table 5, the amount of each ingredient is expressed in the unit of wt%.

TABLE 5 Comp Comp. Ex. 13 Ex. 14 Ex. 15 Ex. 16 Ex. 17 Ex. 5 Ex. 6Precipitated silica 0.00 15.00 15.00 15.00 15.00 0.00 15.00 Glycerin35.00 35.00 30.00 20.00 10.00 5.00 5.00 70% sorbitol solution 45.0045.00 45.00 45.00 45.00 50.00 50.00 Sodium laurylsulfate 2.00 2.00 2.002.00 2.00 2.00 2.00 Sodium saccharin 0.20 0.20 0.20 0.20 0.20 0.20 0.20Paraoxybenzoate 0.15 0.15 0.15 0.15 0.15 0.15 0.15 Xanthan gum 1.00 1.001.00 1.00 1.00 1.00 1.00 Sodium fluoride 0.22 0.22 0.22 0.22 0.22 0.220.22 Vitamin E 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Fragrance 1.00 1.001.00 1.00 1.00 1.00 1.00 Purified water 15.23 0.23 5.23 15.23 25.2340.23 25.23

Examples 18-22 and Comparative Examples 7-8

Each of the toothpaste compositions according to Examples andComparative Examples is obtained from the ingredients and compositionsas shown in the following Table 6. A liquid polyol is mixed with a solidor solidifying polyol first to induce hydrogen bonding, and then powderyingredients including a pharmaceutically active ingredient, xanthan gum,saccharin, preservative and surfactant are dispersed completely into thesolution of a fragrance ingredient, followed by further mixing. Then, ifdesired, a polishing agent, such as silica, and a pharmaceuticallyactive ingredient are introduced thereto and mixed under vacuum toobtain toothpaste compositions.

TABLE 6 Comp. Comp. Ex. 18 Ex. 19 Ex. 20 Ex. 21 Ex. 22 Ex. 7 Ex. 8Precipitated silica 15.00 15.00 15.00 15.00 15.00 15.00 15.00 Glycerin20.00 20.00 10.00 5.00 Polyethylene glycol 300 20.00 10.00 5 Propyleneglycol 20.00 70% sorbitol solution 50.00 50.00 40.00 40.00 40.00 60.0060.00 Erythritol 10.00 Xylitol 10.00 10.00 Sodium laurylsulfate 2.002.00 2.00 2.00 2.00 2.00 2.00 Sodium saccharin 0.20 0.20 0.20 0.20 0.200.20 0.20 Paraoxybenzoate 0.15 0.15 0.15 0.15 0.15 0.15 0.15 Xanthan gum1.00 1.00 1.00 1.00 1.00 1.00 1.00 Sodium fluoride 0.22 0.22 0.22 0.220.22 0.22 0.22 Vitamin E 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Fragrance1.00 1.00 1.00 1.00 1.00 1.00 1.00 Purified water 10.23 10.23 10.2310.23 10.23 15.23 15.23

2. Ratio of Liquid Polyol/Solid (Solidifying) Polyol in Examples andComparative Examples

The ratio of a liquid polyol to a solid polyol in each of Examples andComparative Examples listed in Tables 5 and 6 is determined by using theratio of the number of oxygen atoms to that of carbon atoms. Forexample, the number of oxygen in hydroxyl groups of glycerin is 3 permolecule. In the case of sorbitol, the number of hydroxyl groups permolecule is 6. In the case of 70% sorbitol solution, the ratio iscalculated by multiplying 0.7 to obtain the oxygen mole number based onthe input amount.

$\begin{matrix}{{{polyol}\mspace{14mu} {equivalent}\mspace{14mu} {ratio}\mspace{20mu} \left( {{liquid}\mspace{14mu} {{polyols}/{solid}}\mspace{14mu} {polyols}} \right)} = \frac{\sum\; \begin{matrix}\left( {{Liquid}\mspace{14mu} {polyol}\mspace{14mu} {equivalent}\mspace{14mu} {ratio}} \right. \\\left( {\left( {{{content}/{molecular}}\mspace{14mu} {weight}} \right) \times} \right. \\\left. \left. {{purity} \times {number}\mspace{14mu} {of}\mspace{14mu} {oxygen}} \right) \right)\end{matrix}}{\sum\begin{matrix}\left( {{Solid}\mspace{14mu} {polyol}\mspace{14mu} {equivalent}\mspace{14mu} {ratio}} \right. \\\left( {\left( {{{content}/{molecular}}\mspace{14mu} {weight}} \right) \times} \right. \\\left. \left. {{purity} \times {number}\mspace{14mu} {of}\mspace{14mu} {oxygen}} \right) \right)\end{matrix}}} & \left\lbrack {{Mathematical}\mspace{20mu} {Formula}\mspace{14mu} 1} \right\rbrack\end{matrix}$

TABLE 7 Comp. Comp. Ex. 13 Ex. 14 Ex. 15 Ex. 16 Ex. 17 Ex. 5 Ex. 6 Molarratio of 1.10 1.10 0.94 0.63 0.31 0.14 0.14 liquid polyol/solid polyolComp. Comp. Ex. 18 Ex. 19 Ex. 20 Ex. 21 Ex. 22 Ex. 7 Ex. 8 Molar ratioof 0.35 0.46 0.52 0.52 0.29 0.12 0.07 liquid polyol/solid polyol

As shown in Table 7, the molar ratio of a liquid polyol/a solid polyol(a sugar alcohol) is 0.2 or more in the case of Examples, while themolar ratio is less than 0.2 in the case of Comparative Examples 5-8.

3. Change in Viscosity with Time

The following test is carried out to observe a change in viscosity withtime in Examples and Comparative Examples listed in Table 5 and Table 6.

(1) Determination of Viscosity

Each of the toothpastes obtained according to Examples 13-22 andComparative Examples 5-8 listed in Table 5 and Table 6 is tested rightafter its preparation and after 2 months and 12 months in a pumping typecontainer by determining a change in viscosity. Determination ofviscosity is carried out by using Brookfield viscometer (DV-III UltraRheometer) RVT type, spindle No. 7 under a rotation speed of 10 rpm. Theresults are shown in the following Table 8.

TABLE 8 Viscosity (×1,000 cP) Right after preparation 1 month 12 monthsEx. 13 25.6 34.9 41.5 Ex. 14 25.1 32.3 42.8 Ex. 15 25.6 31.1 41.0 Ex. 1625.2 34.5 40.2 Ex. 17 25.7 31.8 43.5 Ex. 18 25.4 33.2 40.1 Ex. 19 25.832.8 40.6 Ex. 20 25.3 33.1 40.2 Ex. 21 25.5 33.0 43.1 Ex. 22 25.9 34.844.0 Comp. Ex. 5 25.2 54.5 200 or more Comp. Ex. 6 25.5 54.0 200 or moreComp. Ex. 7 25.5 53.9 200 or more Comp. Ex. 8 25.8 54.3 200 or more

When viewed from the amount of sorbitol used in Comparative Examples,the toothpastes cause solidification at their surfaces after the lapseof 12 months at room temperature, and thus viscosity itself cannot bedetermined. Even after 1 month, a rapid increase in viscosity isobserved due to the evaporation of water. However, when the amount of apolishing agent increases, no significant change in viscosity isobserved, suggesting that the amount of a polishing agent has nosignificant effect upon a change in viscosity with time. In addition,when a change is viscosity is observed according to type of polyol, nosignificant change in viscosity is observed. When a small amount ofliquid polyol is used, a rapid change in viscosity is observed withtime. When a small amount of liquid polyol and solid polyol are used atthe same time, viscosity increases rapidly and then solidificationoccurs after the lapse of a long time. It is thought that a small amountof liquid polyol allows the toothpaste composition to maintain ejectionproperty at the initial time but it is difficult to eject the contentsas time goes by. It can be seen from the above test results that thetoothpaste composition disclosed herein undergoes little change inejection property caused by a rapid change in viscosity, when it isapplied to a dip pump. In addition, it can be seen that the combinationof a liquid polyol with a polishing agent allows the use of a dip pumpeven in an air permeable container without any rapid change in viscosityand solidification.

(2) Ejection from Dip Pump

Each of the toothpaste compositions according to Examples 13-22 andComparative Examples 5-8 is received in a 250 mL dip pump container andpumping is carried out continuously so that the remaining amount may be20 gram or less to evaluate the ejection property. The results are shownin the following Table 9.

TABLE 9 Ejection property Initial time 1 month 12 months Ex. 13 Ejectionfinished Ejection finished Ejection finished Ex. 14 Ejection finishedEjection finished Ejection finished Ex. 15 Ejection finished Ejectionfinished Ejection finished Ex. 16 Ejection finished Ejection finishedEjection finished Ex. 17 Ejection finished Ejection finished Ejectionfinished Ex. 18 Ejection finished Ejection finished Ejection finishedEx. 19 Ejection finished Ejection finished Ejection finished Ex. 20Ejection finished Ejection finished Ejection finished Ex. 21 Ejectionfinished Ejection finished Ejection finished Ex. 22 Ejection finishedEjection finished Ejection finished Comp. Ex. 5 Ejection finished 200 mLNot ejectable Comp. Ex. 6 Ejection finished 200 mL Not ejectable Comp.Ex. 7 Ejection finished 195 mL Not ejectable Comp. Ex. 8 Ejectionfinished 190 mL Not ejectable

In the case of Comparative Examples in which the molar ratios ofhydroxyl groups of a liquid polyol/those of a solid polyol are less than0.2, all contents are ejected right after the preparation. However,complete ejection is not allowed after 1 month, ⅕ of the contents remainin the containers, and all Comparative Examples are not ejectable after12 months.

It can be seen that when the molar ratio of hydroxyl groups of a liquidpolyol/those of a solid polyol is less than 0.2, a rapid change inviscosity and solidification occur in spite of the incorporation of aliquid polyol.

On the contrary, Examples show an increase in viscosity due to theevaporation of water but prevents solidification through the hydrogenbonding between hydroxyl groups of a liquid polyol and those of a solidpolyol. According to Examples, all toothpaste compositions leave noresidue after ejection. From this, it could be understood that the rapidchange in viscosity upon the use of a solid polyol, which is an objectto be accomplished by the present invention, is caused since waterevaporates from the solid polyol and thus the solid polyol is exposed tothe surface of a pump and then solidified.

III. Examples 23-29 and Comparative Examples 9-14 1. Composition andPreparation

The oral compositions (Examples 23-29) according to the presentinvention and the comparative conventional oral compositions(Comparative Examples 9-14) are prepared based on the compositions asshown in the following Table 10 and Table 11.

The following method is used: powdery ingredients including saccharin, apreservative and a pharmaceutically active ingredient are dispersed intowetting agents including aqueous sorbitol solution and glycerin, and themixture is diluted with purified water and mixed primarily. Then, apolishing agent such as dental type silica and xanthan gum areintroduced thereto, followed by mixing. Finally, sodium laurylsulfate asa bubbling agent and a fragrance ingredient are added and the resultantmixture is mixed under vacuum to obtain an oral composition. In Table 10and Table 11, the amount of each ingredient is expressed in the unit ofwt %.

TABLE 10 Ingredients Ex. 23 Ex. 24 Ex. 25 Ex. 26 Ex. 27 Ex. 28 Ex. 29Precipitated silica 14.0 14.0 14.0 14.0 14.0 14.0 14.0 Concentratedglycerin 30.0 30.0 30.0 30.0 30.0 30.0 30.0 Aqueous sorbitol 30.0 30.030.0 30.0 30.0 30.0 30.0 solution Sodium laurylsulfate 1.0 1.0 1.0 1.01.0 1.0 1.0 Sodium fluoride 0.22 0.22 0.22 0.22 0.22 0.22 0.22 Fragrance1.0 1.0 1.0 1.0 1.0 1.0 1.0 Saccharin 1.0 1.0 1.0 1.0 1.0 1.0 1.0Xanthan gum 0.5 1.0 2.0 3.0 1.0 1.0 1.0 Thickening polymer 0 0 0 0Sodium Carbomer Gellan gum carboxymethyl 0.3 0.3 cellulose 0.3 Purifiedwater To100 To100 To100 To 100 To100 To100 To100

TABLE 11 Comp. Comp. Comp. Comp. Comp. Comp. Ingredients Ex. 9 Ex. 10Ex. 11 Ex. 12 Ex. 13 Ex. 14 Precipitated silica 14.0 14.0 14.0 14.0 14.014.0 Concentrated glycerin 30.0 30.0 30.0 30.0 30.0 30.0 Aqueoussorbitol 30.0 30.0 30.0 30.0 30.0 30.0 solution Sodium laurylsulfate 1.01.0 1.0 1.0 1.0 1.0 Sodium fluoride 0.22 0.22 0.22 0.22 0.22 0.22Fragrance 1.0 1.0 1.0 1.0 1.0 1.0 Saccharin 1.0 1.0 1.0 1.0 1.0 1.0Xanthan gum 0.3 3.5 0 0 0 0 Thickening polymer 0 0 0 Sodium CarbomerGellan gum carboxymethyl 0.3 0.3 cellulose 0.3 Purified water To100 To100 To100 To100 To 100 To 100

To determine the effects, Examples and Comparative Examples areevaluated in terms of shape retentivity, initial viscosity, a change inviscosity with time and a change in ejectability with time. Convenienceof use and a feeling of use are also evaluated.

2. Test Examples (1) Test Example 1 Evaluation of Shape Retentivity

1) Test Method

The same amount of oral composition is taken from each of Examples andComparative Examples and 1 g of each composition is ejected to each boxof the toothpaste ejection table for determination of shape retentivityas shown in FIG. 3. The initial maximum height and the maximum heightafter 30 seconds are measured to evaluate shape retentivity and shapemaintenance.

FIG. 3 shows a toothpaste ejection table for determination of the shaperetentivity of a toothpaste composition. The table has a width of 2 cm,length of 1 cm, an interval between one box and another box of 0.5 cm,and is printed out in the form of a single page to allow ejection andobservation of various compositions at the same time.

2) Test Results

As can be seen from the following Table 12, addition of xanthan gum to acomposition in an amount of 0.5-3 wt % results in an increase the shaperetentivity and shape maintenance of a composition. Particularly,incorporation of a thickening polymer results in a significant increasein the shape retentivity of an oral composition.

TABLE 12 Change in Height Initial height (cm) Height after 30 seconds(cm) Ex. 23 0.21 0.18 Ex. 24 0.30 0.25 Ex. 25 0.40 0.34 Ex. 26 0.45 0.39Ex. 27 0.42 0.41 Ex. 28 0.43 0.43 Ex. 29 0.43 0.42 Comp. Ex. 9 0.10 0.04Comp. Ex. 10 0.50 0.40 Comp. Ex. 11 0 0 Comp. Ex. 12 0.10 0 Comp. Ex. 130.09 0 Comp. Ex. 14 0.10 0

(2) Test Example 2 Determination of Change in Viscosity

1) Test Method

Each of the oral compositions according to Examples and ComparativeExamples is determined for its initial viscosity right after thepreparation and its viscosity after 4 weeks under the followingconditions.

Conditions for determination of viscosity: BrookField, RV-5, 20 rpm, 5cycles

2) Test Results

As can be seen from the following Table 13, addition of xanthan gum to acomposition in an amount of 0.5-3 wt % results in little change inviscosity with time.

TABLE 13 Change in Viscosity Initial viscosity (cps) Viscosity after 4weeks (cps) Ex. 23 5,000 5,200 Ex. 24 8,000 8,300 Ex. 25 11,000 11,100Ex. 26 20,000 20,500 Ex. 27 11,000 11,200 Ex. 28 10,800 11,100 Ex. 2911,100 11,300 Comp. Ex. 9 3,000 3,500 Comp. Ex. 10 25,000 26,000 Comp.Ex. 11 1,000 1,200 Comp. Ex. 12 2,800 3,000 Comp. Ex. 13 2,600 2,800Comp. Ex. 14 3,000 3,100

(3) Test Example 3 Change in Electability with Time

1) Test Method

Each of the compositions according to Example 25 and ComparativeExamples 10-14 is charged to a dip tube type pumping container andstored at 50° C. and at room temperature. The ejectability of eachproduct is observed at the initial time, after 2 weeks and after 4weeks.

2) Test Results

As can be seen from the following Table 14, addition of xanthan gum to acomposition in an amount of 0.5-3 wt % results in excellent ejectabilityand pump restorability.

Particularly, in Comparative Example 9 containing 0.3 wt % of xanthangum and Comparative Examples 11 and 12 containing no xanthan gum, thecontents flounce toward different directions upon ejection due to theirlow viscosity. In the case of Comparative Example 10 containing 3.5 wt %of xanthan gum, the contents cannot be ejected but the pump is damagedafter 4 weeks, as shown in FIG. 4.

TABLE 14 Initial time After 2 weeks After 4 weeks Ex. 25 50° C. Ejectionfinished Ejection finished Ejection finished Room temp. Ejectionfinished Ejection finished Ejection finished Comp. Ex. 9 50° C. Ejectionfinished/ Ejection finished/ Ejection finished/ Contents flounceContents flounce Contents flounce Room temp. Ejection finished/ Ejectionfinished/ Ejection finished/ Contents flounce Contents flounce Contentsflounce Comp. Ex. 10 50° C. Ejection finished Hardly ejected Notejectable Room temp. Ejection finished Hardly ejected Not ejectableComp. Ex. 11 50° C. Ejection finished/ Ejection finished/ Ejectionfinished/ Contents flounce Contents flounce Contents flounce Room temp.Ejection finished/ Ejection finished/ Ejection finished/ Contentsflounce Contents flounce Contents flounce Comp. Ex. 12 50° C. Ejectionfinished/ Ejection finished/ Ejection finished/ Contents flounceContents flounce Contents flounce Room temp. Ejection finished/ Ejectionfinished/ Ejection finished/ Contents flounce Contents flounce Contentsflounce

(4) Test Example 4 Comparison of Feeling of Use and Convenience of UseThrough Consumers' Evaluation

1) Test Panels

Thirty test panels are recruited from male and female adult volunteersin their twenties and thirties.

2) Test Method

A new paste is supplied to the test panels weekly and the test panelsare allowed to use the corresponding toothpaste only. Then,questionnaire is carried out to evaluate a feeling of use andconvenience of use.

3) Toothpaste for Test

Each of the compositions according to Example 25 and ComparativeExamples 9-12 is received in a dip tube type pump container and issupplied to the test panels as toothpaste for the test. All compositionshave the same fragrance and color to prevent the likes and dislikes ofthe test panels based on a fragrance or color in advance.

4) Question Items

Evaluation is carried out by using the questionnaire for consumers'evaluation as shown in FIG. 5.

5) Test Results

After carrying out the test, it can be seen that the compositionaccording to Example 25 provides the best results in terms ofconvenience of use (ejectability), appearance of toothpaste,releasability of toothpaste, cleaning quality and overall satisfactionlevel, as shown in FIG. 6.

The present disclosure has been described in detail. However, it shouldbe understood that the detailed description and specific examples, whileindicating preferred embodiments of the disclosure, are given by way ofillustration only, since various changes and modifications within thescope of the disclosure will become apparent to those skilled in the artfrom this detailed description.

1. A pumping type toothpaste product comprising a toothpastecomposition, wherein the composition comprises a lubricant.
 2. Thepumping type toothpaste product according to claim 1, wherein thetoothpaste composition comprises the lubricant and a polishing agent. 3.The pumping type toothpaste product according to claim 2, wherein thepolishing agent is present in an amount of 0.1-30 wt % based on thetotal weight of the toothpaste composition.
 4. The pumping typetoothpaste product according to claim 2, wherein the polishing agent isany one selected from the group consisting of calcium monohydrogenphosphate, precipitated silica, fumed silica, colloidal silica, zeolite,calcium carbonate, hydrous alumina, kaolin, cellulose and a mixturethereof.
 5. The pumping type toothpaste product according to claim 2,wherein the lubricant is present in an amount of 30-85 wt % based on thetotal weight of the toothpaste composition.
 6. The pumping typetoothpaste product according to claim 2, wherein the lubricant functionsto prevent a piston from being worn by the polishing agent.
 7. Thepumping type toothpaste product according to claim 1, wherein thelubricant contained in the toothpaste composition is a liquid polyol. 8.The pumping type toothpaste product according to claim 7, wherein thetoothpaste composition comprises the liquid polyol and the polishingagent.
 9. The pumping type toothpaste product according to claim 8,wherein the liquid polyol is any one selected from the group consistingof polyethylene glycol (PEG) 200-600, glycerol, propylene glycol,ethylene glycol, polypropylene glycol and a mixture thereof.
 10. Thepumping type toothpaste product according to claim 8, wherein the liquidpolyol functions to prevent a piston from being worn by the polishingagent and to allow the toothpaste product to maintain its viscosity. 11.The pumping type toothpaste product according to claim 7, wherein thetoothpaste composition comprises the liquid polyol and a sugar alcohol.12. The pumping type toothpaste product according to claim 11, whereinthe sugar alcohol is erythritol, arabitol, xylitol, ribitol, sorbitol,mannitol, galactitol, maltitol, lactitol or a mixture thereof.
 13. Thepumping type toothpaste product according to claim 11, wherein theliquid polyol is polyethylene glycol 200-600, glycerol, propyleneglycol, ethylene glycol, polypropylene glycol or a mixture thereof. 14.The pumping type toothpaste product according to claim 13, wherein theliquid polyol is glycerol, polyethylene glycol 300 or a mixture thereof.15. The pumping type toothpaste product according to claim 11, whereinthe sugar alcohol is present in an amount of 1-60 wt % based on thetotal weight of the toothpaste composition.
 16. The pumping typetoothpaste product according to claim 11, wherein at least one hydroxylgroup of the sugar alcohol forms hydrogen bonding with hydroxyl or ethergroups of the liquid polyol.
 17. The pumping type toothpaste productaccording to claim 11, wherein the liquid polyol is present in an amountof 10-85 wt % based on the total weight of the toothpaste composition.18. The pumping type toothpaste product according to claim 11, whereinthe mole number of the hydroxyl or ether groups of the liquid polyolforming hydrogen bonding with the hydroxyl groups of the sugar alcoholis at least 0.2 times of the hydroxyl groups of the sugar alcohol.
 19. Agel-like toothpaste composition comprising a polishing agent and aliquid polyol and having excellent viscosity retentivity.
 20. Thegel-like toothpaste composition according to claim 19, wherein thepolishing agent is present in an amount of 0.1-30 wt % based on thetotal weight of the toothpaste composition.
 21. The gel-like toothpastecomposition according to claim 19, wherein the liquid polyol is presentin an amount of 30-85 wt % based on the total weight of the composition.22. The gel-like toothpaste composition according to claim 19, whereinthe liquid polyol functions to prevent the toothpaste composition fromdrying and/or to inhibit an increase in viscosity of the toothpastecomposition.
 23. The gel-like toothpaste composition according to claim19, which shows a change in viscosity of 100-15,000 cP.
 24. An oralcomposition provided with elasticity based on xanthan gum.
 25. An oralcomposition comprising xanthan gum and a thickening polymer.
 26. Theoral composition according to claim 25, wherein the thickening polymeris at least one selected from the group consisting of starch, carbomer,gellan gum, gelatin, guar gum, locust bean gum, alginic acid, Arabicgum, carrageenan, agar, pectin, rheogic, cellulose and derivativesthereof.
 27. The oral composition according to claim 26, wherein thecellulose and derivatives thereof comprise any one selected from thegroup consisting of sodium carboxymethylcellulose, hydroxymethylcellulose, hydroxypropylmethyl cellulose, methylethyl cellulose and amixture thereof.
 28. The oral composition according to claim 25, whereinthe xanthan gum is present in an amount larger than 0.5 wt % and lessthan 3 wt % based on the total weight of the composition, and thethickening polymer is present in an amount of 0.05-1 wt % based on thetotal weight of the composition.
 29. The oral composition according toclaim 25, which has a viscosity of 5,000-20,000 cP under the conditionsof 25° C., BrookField, RV-5, 20 rpm.
 30. The oral composition accordingto claim 25, which has an initial height of 0.15-0.55 cm and a height of0.1-0.45 cm after 30 seconds, when it is ejected in an amount of 1 g toan area having a width of 2 cm and a length of 1 cm from a containerhaving a diameter of 0.3-1.0 cm.
 31. A toothpaste composition comprisingxanthan gum in an amount larger than 0.5 wt % and less than 3 wt % andhaving a viscosity of 5,000-20,000 cP under the conditions of 25° C.,BrookField, RV-5, 20 rpm.
 32. The toothpaste composition according toclaim 31, which further comprises a thickening polymer.
 33. Thetoothpaste composition according to claim 32, wherein the thickeningpolymer is present in an amount of 0.05-1 wt % based on the total weightof the composition.
 34. The oral composition according to claim 31,which has an initial height of 0.15-0.55 cm and a height of 0.1-0.45 cmafter 30 seconds, when it is ejected in an amount of 1 g to an areahaving a width of 2 cm and a length of 1 cm from a container having adiameter of 0.3-1.0 cm.
 35. A pumping type toothpaste product comprisingthe toothpaste composition as defined in claim 31.